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At the molecular level, phosphorylation-dephosphorylation allows fast and sensitive regulation of enzyme activity.
This belongs to a family of cytokines subject to stringent and sensitive regulation, and might therefore be particularly susceptible to optimization-induced effects.
However, our starvation experiments clearly showed a sensitive regulation of the mptABC operon by zinc but not by iron.
Indeed, our results suggested that a site ~13 bp inside the upstream border of the +1 nucleosome is a sensitive regulation point in the yeast genome.
It has previously been reported that perturbations in the redox metabolism can induce changes in gene expression thereby reflecting redox sensitive regulation mechanisms [ 41].
Sensitive regulation of L-arabinose metabolism with AraR as the key repressor has been observed and characterized in Bacillus subtilis [ 49] as well as C. acetobutylicum [ 47, 48].
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Our data suggest that gp150 works not by providing strong binding, but by providing glycosaminoglycan-sensitive regulation of cell binding by another virion glycoprotein, possibly gB [27], [31].
Tension-sensitive regulation of TβR spatial organization.
We demonstrate tension-sensitive regulation of endogenous downstream Smad3 phosphorylation by cellular tension and TGFβ.
Figure 7 shows the tension-sensitive regulation of endogenous Smad3 phosphorylation by cellular tension and TGFβ.
The only PVH gene that showed glucose-sensitive regulation in female offspring from HFD-fed dams was Crh.
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