Sentence examples for sensitive progression from inspiring English sources

Extensive-stage small-cell lung cancer (SCLC) patients who progress after platinum-based chemotherapy are traditionally categorized as platinum sensitive (progression ≥ 90 days from last platinum dose) or refractory (progression < 90 days), a practice arising from seminal observations of worse survival in refractory patients.

We show modification of PDE4D7 in this way occurs under basal conditions, reduces PDE4D7 activity, and we hypothesise that this feature allows basal cAMP signalling, which may be necessary for cellular homeostasis and could be involved in the cAMP sensitive progression of prostate cancer from the androgen sensitive to androgen insensitive state.

It is evident that the AA system is able to differentiate between patients with early PCO and no PCO and also to be sensitive to progression of PCO.

Although standard clinical outcomes have been shown to be less sensitive to progression than biomarker outcomes in MCI and pre-MCI populations, non-standard scoring has improved the performance of the Alzheimer's Disease Assessment Scale cognitive subscale, making it more sensitive to progression.

Quantitative measurement of JSW may be a more sensitive measure of progression in hand OA, but the sensitivity to change must be explored in future longitudinal studies.

He chose to study two indicators of linguistic ability thought to be sensitive to the progression of dementia, idea density and grammatical complexity.

Positive TST and QFT tests were moderately sensitive predictors of progression to microbiologically confirmed TB disease.

All together, we have documented a powerful advance in our visualization of tumor biology dynamics, which allows for sensitive monitoring cancer progression or favorable response to therapy.

Chen et al. used a constant speed (5 or 15 rpm) rotarod protocol whereas Smith et al. (as in our study) used an accelerating rotarod, which may be a more sensitive indicator of progression of disease motoric dysfunction in the R6/2 mouse [52].

Since the publication of these criteria, it has become evident that the physiological markers are more specific to the AD bio logical process; topographic markers are more sensitive to disease progression but less specific to AD [ 13].

Because there are no validated biomarkers in AD, it is important to seek out clinical outcomes that are also sensitive for measuring progression in these very early stages of disease.