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Moreover, for applied work, serious epistemological hurdles may ultimately lead us to drop the responsibility-sensitive principle for practical reasoning about the actual world.
Whereas if you're in the middle you have to sort of say, Well, we have to use power, but we have to be sensitive to principle, and you have to sometimes deal with dictators, yet promote democracy, and sometimes you have to use force, but generally speaking you have to be careful not to be excessive.
Although both assays are potentially rapid and sensitive, their principles of detection and optimisation are different, as is the resulting price per assay.
Wang and Hannafin (2005) defined design-based research as 'a systematic but flexible methodology aimed to improve educational practices through iterative analysis, design, development, and implementation, based on collaboration among researchers and practitioners in real-world settings, and leading to contextually-sensitive design principles and theories (p. 6)'.
Complementary elements in ethical decisions also include context-sensitive ethical principles or norms (see below).
"We are very sensitive to the principle of 'First, do no harm.' ".
In the same way as a plant germinates from a seed, the vegetative and sensitive souls (the principle of life) exist in an inchoate state in the semen separated from the father, and they are educed from this matter by the action of the corporeal spirit (the power of the principle of life D43Q 37, 37; QLIIS 85, 239).
Our findings provided empirical support to lifetime QALY prioritarianism primarily in two ways: by favoring a principle sensitive to lifetime QALYs over pure QALY maximization and by favoring a monotonically decreasing priority pattern across initial lifetime QALYs over other patterns.
Although it is unquestionable that invertebrates are in principle sensitive to EDCs, their use as standard biotest organisms has been impeded by the lack of laboratory cultures and detailed insights into invertebrate endocrinology.
Thus, the totality of the reviewed studies suggests that the increased aldehyde yields determined in the chemical analyses did not increase the activity of the smoke in toxicological assays that are in principle sensitive to their activity.
These data support that the upregulation of HLA-E on myeloma cells that are in principle sensitive to NK cell kill, renders these cells resistant to NKG2A+ NK cells, indicating that the selection of NKG2A-negative NK cells is essential to efficiently eliminate HLA-E positive myeloma cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com