A simple, rapid, precise, accurate and sensitive high performance liquid chromatographic method has been developed for simultaneous determination of ACE inhibitors with hydrochlorothiazide and indapamide in pharmaceutical formulations.
The change in fluorescence spectra when MU-P is converted to MU allows for quantification of entrapped (MU-P) and released (MU) liposome contents by fluorescence or by a sensitive high performance liquid chromatography assay.
Novel, simple and sensitive high performance thin-layer chromatography (HPTLC) with fluorescence detection has been successfully developed and validated for determination of gemifloxacin mesylate (GFX) in plasma samples without prior pretreatment.
A fast and sensitive high performance reversed-phase liquid chromatography tandem mass spectrometry method was developed and validated for the analysis of 15 prescription pharmaceuticals and four of their metabolites in influent wastewater.
A capillary hexyl methacrylate monolithic column was designed and prepared for simple, rapid, economical and sensitive high performance liquid chromatography method for the determination of caffeine in food, using a water/acetonitrile (90 10, v/v) mobile phase with ultraviolet (UV) detection.
Thus, efficient regio- and chemoselective immobilization of proteins to minimize nonspecific binding in random orientations is important for developing sensitive high performance biosensors.
