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Discussion Patients having a chronical hepatopathy have a more frequent bacterial colonization due to preoperative sensitive germs.
We have also gathered bacterial colonization data before and after the transplantation by distinguishing the multiresistant bacteria and the sensitive germs.
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This last event is dependent on a reduction in the number of spermatogonia, which appear to be the most sensitive germ cell type to cisplatin.
As feeding on LF82 did not prevent the formation of nematode progeny (data not shown), we used the temperature-sensitive germ-line mutant glp-4 in order to ensure a defined number of age synchronized nematodes for the duration of the killing experiments.
miR-10b was observed to be consistently high in all the cisplatin resistant sublines derived from parental cisplatin-sensitive germ cell tumor cell lines [ 35], and it was reported to confer resistance to 5-fluorouracil in colorectal cancer cells [ 36].
Second is that samples are usually drawn from peripheral blood; these would only be sensitive to germ-line mutations.
On the other hand oogonia may be less sensitive than male germ cells to some gonotoxic insults (e.g. Guerquin et al., 2009).
In addition, 56.6% of germs were sensitive to nalidixic acid and 56.6% to biseptol.
Furthermore, the findings above indicate that the clustering of gene expression profiles from testicular biopsies is extremely sensitive to the relative germ cell composition, a property that enables us to select homogeneous samples from the clustering outcome.
If you have a germ-sensitive job (e.g., healthcare worker), you may want to use the more conservative WHO guidelines for hand-washing.[3].
As explained by Dr. Stefania Gonfloni (University of Rome Tor Vergata and LBMCC, Luxembourg), germ cells are sensitive to genotoxins and oocytes of women treated with chemotherapeutic agents are massively degraded.
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