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It is practical but not sensitive for assessment of lower limb function and does not assess upper limb function.
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This underscores the importance of using sensitive methods for assessment of β-cell function and insulin sensitivity in pathophysiologic studies.
To conclude, microdialysis and PET ([18 F]FDOPA and [11C]DTBZ) are sensitive techniques for assessment of the functionality of the dopaminergic system and may both be crucial in furthering our understanding of diseases such as Parkinson's.
This study was designed to investigate whether functional and molecular MRI techniques are sensitive biomarkers for assessment of neuroinflammation and drug efficacy after traumatic brain injury (TBI) in rats.
Quantitative measures of osteoporosis may thus be a more sensitive tool for assessment of inflammatory bone involvement in RA.
Isolation of CTCs is expensive and labour-intensive, so we assessed whether free DNA isolated from plasma would be a more sensitive technique for assessment of mGSTP1 levels.
This study has demonstrated that the MFNU is a sensitive instrument for assessment of functional problems in boys with HKD associated with motor inhibition and stability.
This first psychometric assessment of a translated WOSI score shows that it is a valid, reliable and sensitive instrument for assessment of groups of patients, and in some respects also for individual patients with shoulder problems associated with instability.
Using a sensitive ELISA for assessment, the level of activated rFIXFc was found to be consistently low (0.002 0.004 mol%) in the validation batches (Table 3), which were significantly lower than levels reported for an approved rFIX product 11.
Although the present study was limited by the small sample size, we believe that glucose metabolism (SUV) measured on MRI/PET fusion images is suitable for visualization of the metabolic activity of neural tissue, and that F-FDG PET is a more sensitive tool for assessment of the clinical outcome and prognosis in patients with cervical compressive myelopathy.
The effects of C13 on Pgp function were determined by comparison with Pgp modulator Vp on intracellular accumulation of Rh123 fluorescence, a sensitive assay for assessment of Pgp function and the results were expressed as ratios of MCF of Rh123 (Hu et al, 1999a).
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