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"Because the State intends to seek a protective order to restrict the dissemination of such sensitive discovery in this matter," she wrote, "the State was not willing to so barter, and so no agreement could be reached".
A novel phylogenetic footprinting approach was developed for the sensitive discovery of conserved cis-regulatory elements even in diverged sequences.
From the point of view of data analysis, we believe that intelligent post-processing of search results is a promising resolution to sensitive discovery of novel peptides and genes.
Instead of using the protein-protein interaction databases we could, instead, use functional linkage networks, which have more comprehensive coverage of a broad variety of gene relationships, and could allow for more sensitive discovery of network signatures under various conditions of interest [ 62].
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(If you have a unique, time-sensitive discovery, though, patent it first, he adds).
Data Security Intelligence promises to be the next big thing that provides a more automated and data-centric view into sensitive data discovery, classification and risk assessment.
To capture the evolutionary behavior of the repeated units in a systematic fashion, we built a framework for short sensitive repeat discovery (see Materials and Methods).
We believe a hybrid approach that integrates multiple signals from all three sources (gapped alignment, split reads and de novo assembly) allows for more sensitive indel discovery than methods examining merely one or two signals.
We used sensitive repeat discovery and evolutionary reconstruction to show that the KNL1 repeat arrays have undergone extensive, often species-specific array reorganization through iterative cycles of higher order multiplication in conjunction with rapid sequence diversification.
cnvHap has been shown to be one of the most sensitive CNV discovery and genotyping algorithms, due to its flexible modelling of intensity data (in this case read-depth data) across an entire population.
We screened both compounds against a collection of 4700 homozygous deletion strains (Giaever et al. 2002; Giaever et al. 2004; Hillenmeyer et al. 2008; Hoon et al. 2008; Lee et al. 2005b) and identified 458 deletion strains that were significantly sensitive (false discovery rate < 0.05) to either MG or GLY (supporting information, Table S1 and Table S2).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com