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This system allows the accurate and sensitive differentiation of 5mC from the four deoxyribonucleosides, the four ribonucleosides and 5hmC [ 21].
This method was tested on 297 samples from Thailand and enabled highly sensitive differentiation and separate quantitation of mixed parasite infections in a single reaction.
This may in part be due to in sensitive differentiation from other VGS using standard practice of bile solubility, optochin susceptibility and colony morphology [ 19].
This study used 3 T MRI with an optimised protocol and careful positioning of the MTP joints to allow better visualisation of the plantar plates and more sensitive differentiation of pathology [ 16].
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If such sensory-sensitive differentiation occurs early in development, this might explain why there is no significant deafening effect on some of the males.
Moreover, these MYB knock-down cells are more sensitive to differentiation after exposure to low doses of differentiation-inducing agents, and can be driven into apoptosis with doses that would normally only induce differentiation.
NB is a common pediatric malignancy characterized by tremendous clinical heterogeneity, in which some tumors are extremely aggressive and drug resistant while others can spontaneously differentiate into benign forms and are sensitive to differentiation stimuli [ 6].
On the other hand, mouse ES cells that constitutively express Nanog are less sensitive to differentiation signals and do not require LIF to maintain an ES cell identity [2].
Here, we use a similar reporter vector sensitive to differentiation specific miRNAs to show that a single vector bearing multiple miRNA target sequences conjugated to different reporters can be used to monitor hiPSC formation from human fibroblasts and subsequent differentiation of the hiPSC.
Statistical parsimony tended to be more sensitive to differentiation among putative species lineages within A. binghami and E. socotrensis.
Peripheral blood monocytes can be reprogrammed to generate a kind of stem cell-like cell (PCMO), which is sensitive to differentiation into hepatocyte-like cells [ 2, 3].
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