Exact(2)
Menthol acts on the highly sensitive cold receptor TRPM8 located on the cell membrane of sensory neurons (McKemy et al. 2002).
The US LAIV backbone (or the master donor virus) was generated by serial passage of an influenza A strain (A/Ann Arbor/6/60 H2N2) and an influenza B strain (B/Ann Arbor/1/66) at lower temperatures in primary chick kidney cells, resulting in viruses that are temperature sensitive, cold adapted, and attenuated [ 9, 10].
Similar(58)
Importantly, 4/61 (6%) were re-classified from wild type to mutant by the more sensitive COLD-PCR melting curve method.
The resulting 6∶2 reassortant vaccine virus is a temperature-sensitive, cold-adapted, attenuated virus that is grown in chicken eggs using the same manufacturing process used to produce MedImmune's seasonal trivalent LAIV.
Only the tooth 47 showed percussion sensitivity and was not sensitive to cold.
Thirdly, populations in subtropical regions may be more sensitive to cold spells and lack necessary preparedness because cold spells are not common in these regions.
Several years ago I read an article that some people who are very sensitive to cold water may sustain a heart attack from submersion into cold water.
In fact, mechanoreceptor nerve fibres that are sensitive to cold have increased spontaneous discharge frequency in the presence of cold stimuli.
They are extremely sensitive to cold drafts.
Inca Doves are sensitive to cold and use several means to survive it.
Tomatoes especially are sensitive to cold nights and will not flower or set fruit.
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