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Nuclear erythroid-2-related factor 2 (Nrf2) is a redox-sensitive, basic leucine zipper protein that regulates the transcription of several antioxidant genes.
On the contrary, a probe molecule specific and highly sensitive for basic sites is missing.
PROP is a bitter thiourea compound; tasters have a greater number fungiform papillae and taste buds on these papillae, making them more sensitive to basic tastes, including fat.
In fact, tumor cells which are highly dependent on glycolysis are more sensitive to basic nutrient deprivation such as glucose [ 48].
The resulting functionalised indenes were found to be sensitive to basic conditions: C-sulfonylated indene-1-amine (4) was isolated in good yield when chromatographic purification of 2 c was attempted using triethylamine-treated silica gel to improve separation (Scheme 4), and could be deliberately prepared from 2 c.
Nuclear factor erythroid-2 (NF-E2 -related NF-E2 -related), a member of the cap 'NF-E2 -relatedly ofactorx-sensitive bZIP (basic leucine zipper) proteins, is the major transcriptional regulator of the expression of genes encoding phase II detoxifying/antioxidant enzymes, including heme oxygenase-1 (HO-1) [ 7].
Most Americans, with immigrant stories in our own backgrounds, are sensitive to this basic injustice.
Social media research has to move beyond an obsession with ever bigger numbers, and become sensitive to our basic task – the messy, challenging task of understanding human beings through their everyday, lived experiences.
Then, when it became clear that it was desirable to lock away some sensitive information, a basic username and password system was developed.
But Taiwan's telecom regulator and the overseer of Taiwan's mainland relations said in a legislative hearing Thursday that Taiwanese law does not allow mainland investment in sensitive sectors like basic telecom infrastructure.
For example, binding sites of Forkhead box (Fox) transcription factors are enriched in demethylation sensitive genes whereas basic Helix-Loop-Helix (bHLH) transcription factor binding sites are enriched in demethylation resistant genes.
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