Recent modifications to the method render it less sensitive to assumption but the modified method remains sensitive to the assumption that exposure is not event dependent in the case of hip fracture and TZDs this assumption cannot be made; TZD exposure is less likely once fracture has occurred [ 23].
The design is highly dependent on failure consequence and moderately sensitive to assumption of structural life span and discount rate.
Sensitivity analyses showed that the model is highly sensitive to assumptions about provider reimbursement, particularly assumptions regarding the level of office visit code reimbursed.
Where estimated ICERs were likely to be sensitive to assumptions around health gains or recidivism, we tested these assumptions in sensitivity analysis.
Indeed, the sensitivity analyses show that the model is sensitive to assumptions about coverage of services and level of reimbursement, and the gap between provider costs and reimbursement would increase significantly under differing assumptions.
For both FCS and HDDS outcomes, one-way sensitivity analyses showed that the model was most sensitive to assumptions about these outcomes (i.e. the probability of participant or comparator households achieving adequate FCS and high HDDS).
Re "When Talk of Guns and Butter Includes Lives Lost" (Economic View, Jan . 15, which included our paper in its discussion of how economists value the costs of the Iraq war: Because estimates of war costs are so sensitive to assumptions, we built an online cost estimator that allows users to change those assumptions and then see how those changes affect estimated future costs.
The first three sensitivity analyses clearly show that the impact of MC is very sensitive to assumptions about the degree of protection (relative risk) afforded by male circumcision, especially in terms of female-to-male transmission.
The ICERs were most sensitive to assumptions concerning the quality of life of the HCV health states and least sensitive to assumptions concerning the quality of life of patients on treatment for those who receive BOC/RGT, and quality of life of the general population for patients who receive BOC/PR48.
Almost all of the budget is highly sensitive to assumptions about economic growth, inflation and interest rates.
