Sentence examples for sensitive activation from inspiring English sources

We suppose that combination of unique properties based on MDR inhibition, stimuli sensitiveness (pH sensitive activation of drug), improved pharmacokinetics and increased uptake into the cells made the described polymer micelle a good candidate for investigation as potential drug delivery system.

Thus the lack of 3D SfS sensitive activation in the IPS is not due to the analysis procedures we used.

Selection of positive clones was mediated through the temperature sensitive activation of the RAS-pathway by recruitment of SOS-tagged bait which allows yeast growth.

Consistent with this, cytometric analysis of diss. 1 A.12 revealed similar (albeit slightly less sensitive) activation parameters than the corresponding clone from the LN8 library.

For example, WNT2 dependent, sFRP1 sensitive, activation of c-jun/AP-1 contributes to cell invasion (Le Floch et al, 2005), which may explain the requirement for c-jun action in intestinal tumorigenesis in mice (Nateri et al, 2005).

By the use of specific inhibitors, we excluded the previously reported mechanisms of LL-37, that is the release of EGF-like factors through activation of metalloproteases and/or pertussis toxin sensitive activation of G proteins.

The transcription factor NF-κB is an example of distinct redox-sensitive activation and DNA binding [57]; it is activated by various physiological stimuli known to produce ROS; on the contrary, to permit DNA binding, similar to Fos, Jun, and Nrf2, cysteine residue within DNA binding domain must be reduced.

For example, RAC1, MAPK1, MAP2K, MAP4K were all induced by UA and are known to exhibit redox-sensitive activation that in turn promotes phospho-activation of p38 and ERK-1/2 MAPK[151].

In this way of comparing calculation with experiments, fragile behavior begins at the onset of temperature-sensitive activation around the characteristic temperature T*.

A significant magnitude X outcome interaction (F 1,45)  = 7.071, P<.05) indicated that the outcome-sensitive activation was more pronounced in $5 trials compared to 50¢ trials.

Hypertension-induced cerebrovascular oxidative stress and redox-sensitive activation of matrix metalloproteinases (MMPs) were increased in aging.