Sentence examples for sensitising factor from inspiring English sources

Outcomes indicated β-Lg 127 135 as a possible "immune sensitising factor" in vivo.

The central role of caspase 8 was further indicated by our observation that cisplatin-induced DR5 upregulation was not an important sensitising factor.

44 47 These findings indicate that occupational health practitioners are justified in adopting a prudential attitude towards atopic participants exposed to a sensitising risk factor, even though this is not the only consideration, because many workers develop symptoms after the beginning of exposure that need to be promptly interpreted.

Since, however, oncogenic MYC is only one factor sensitising cancer cells to BET inhibition and considering its high expression levels in most tumours it is not likely that this oncogene will have predictive value for patient stratification.

Apoptosis-inducing factor markedly sensitised the resistant cells to CDDP-induced apoptosis in a concentration-dependent manner (*** P<0.001; Figure 3C).

In this study, we showed that cells with increased NF- κB activity are less sensitive to ansamycins and that inhibiting the constitutive activity of this transcription factor can sensitise CRPCs to 17-AAG.

Cells expressing the longest form of caspase-cleaved GRASP65 (N393) were only marginally sensitised, suggesting that factors between amino acids 320 and 393 are responsible.

One factor which may sensitise cells to increased DNA damage is impaired mitochondrial function [74].

As an example, the multi-kinase inhibitor sorafenib, recently approved for the treatment of renal cancer and currently undergoing clinical trials for a wide range of human cancers, downregulates Mcl-1 and cellular inhibitor of apoptosis-2 expression sensitising cancer cells to tumour necrosis factor (TNF -related apopTNF -relatedng ligapoptosis-inducingd celigandTRAIL -inducedl, 2007).

The data suggest that PL may act through interfering with antiapoptotic factor c-FLIPL to sensitise Dox-mediated apoptotic signalling.

For comprehensiveness, it was continuously sensitised over infinite scale as an explicit factor dependent on in-situ spatio-temporal injectant state perplexity with discrete slope and altitude for each polymeric character.