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Sensitisation was not a problem in single-pass hardening.
Sensitisation was due to chromium carbide formation at the grain boundaries.
The FP6 project CAESAR was aimed at developing QSAR models for 5 key toxicological endpoints of which skin sensitisation was one.
Different laser parameters were compared and their influence on hardness, microstructure, geometry of the hardened zone and sensitisation was investigated, especially for overlapping passes.
The AFP model for skin sensitisation was built on the training set by using the following parameters: maximal number of rules for each chemical activity = 30; minimal number of compounds for a given rule = 2; maximal number of cuts for each axis = 5.
Complete abolition of DRB-induced UV sensitisation was not observed, which may be a result of incomplete synchronisation.
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Sensitisation is detectable by reaction to a skin-prick test.
In the appeal court judgment, Lord Sales said: "On the medical evidence, platinum sensitisation is not harmful in itself in any relevant sense.
The mechanism of the drug sensitisation is not clear.
The skin sensitisation is a well defined endpoint of specific utility within the REACH framework.
Stress sensitisation is thought to be an underlying mechanism and may be reflected in an altered autonomic stress response.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com