These include protocols for sensitisation and methods for measuring the extent of disease, such as lung inflammation, AHR, and others.
The final models, accessible from CAESAR website, offer a robust and reliable method of assessing skin sensitisation for regulatory use.
The final models, accessible from the CAESAR website [2], offer a robust and reliable method of assessing skin sensitisation for regulatory use.
There is a pressing need for non-animal methods to predict skin sensitisation potential and a number of in chemico and in vitro assays have been designed with this in mind.
TB-specific interferon-γ release assays (IGRAs) are sensitive and specific methods for detecting immune sensitisation by TB [ 3], and have accurately characterised the epidemiology of LTBI amongst high risk populations such as recent immigrants or TB contacts.
It is relevant to consider whether advances in immunobiology provide opportunities also for the design of alternative approaches to the toxicological evaluation of skin sensitisation, including the development of in vitro methods.
Computerised pneumatic cuff pressure algometry (CPA) is a method for assessing temporal summation (ie, degree of central sensitisation).
Scientific and social science methods were used to collect data, following full sensitisation of the communities.
However, CHAs conduct multiple tasks, including sensitisation campaigns on prevention of malaria, enhancing sanitation standards, use of family planning methods, and HIV/AIDS prevention.
One effective method has been to ensure the inclusion of both men and women during gender sensitisation, in order to acquire the buy-in of the most influential members of communities, such as religious and customary leaders, who are generally male.
