Disease severity was scored by the Scoring of Atopic Dermatitis (SCORAD) index and sensitisation was evaluated by standard prick test (SPT) and specific IgE (sIgE) measurements [ 14].
Two separate measures of pain behaviour were assessed: change in hind limb weight distribution, which is a behavioural correlate of hyperalgesia, and hind paw mechanical withdrawal thresholds, which provide an index of central sensitisation.
Evaluation of central pain sensitisation in patients with few inflammatory indices may be a predictive tool regarding the effect of anti-inflammatory treatment.
19 On the basis of these findings, we hypothesise that facilitated temporal summation (ie, central sensitisation) in combination with low inflammatory indices in patients with RA at baseline predicts poorer treatment response following the initiation or intensification of medical treatment.
Published data suggest that sensitisation to SM develops more frequently in patients who are already sensitised to allergens of HDM. 17 18 Sensitisation to SMs in the absence of sensitisation to Dermatophagoides spp has been proposed as a rare event.
Sensitisation is detectable by reaction to a skin-prick test.
These range from more CCTV cameras in city centres to gender sensitisation lessons for schoolchildren.
She and other activists are also contacting colleges to help run gender sensitisation classes.
But much longer-term support, strengthening and community sensitisation will be needed.
After several weeks of sensitisation, mobilisation and assessments, the people have been anxious to see real action.
