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The only realistic path is a sensible variant on what Mr. Cruz said this morning: Listen to the public and stop governing by crisis.
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Although considerable progress is being made, in light of the limitations in the various methodologies reviewed here, we suggest that careful integration of annotations and predictions from a range of tools is a sensible strategy in practical variant-prioritization scenarios.
Since collecting family history is an important part of standard medical assessment, and can contribute independent genetic information beyond GWAS variants, it seems sensible to incorporate it into genetic risk prediction.
This week I've been driving Lexus's 250 ISC – the convertible variant of the sublimely sensible and wonderfully driveable IS range.
Although Tajima's D and HKA tests were not significant, the Fay and Wu's H test which is designed to be sensible to an excess of high frequency derived variants was significantly different from zero (H = −8.52, P = 0.04).
Islamism in the Arab world now covers a wide spectrum; and its sensible end has fast been evolving from a radical, violent strain into a modern, outward-looking variant.
Until whole genome sequencing for large cohorts becomes affordable sequencing "extended" exomes seems to provide a sensible way to reduce costs while maximizing the chances of detecting disease-associated variants.
But sensible?
Be Sensible.
Sensible question.
Perfectly sensible".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com