He told BBC Radio Ulster's Sunday Sequence: "Any sensible, right-minded person watching that video clip would form an opinion and that is not the opinion I would want for the Ulster Unionist Party.
One has to consider whether a concatenation of molecular sequences is sensible or whether different segments should be separately analyzed.
A tree would be interesting (a) to see how much sensible evolutionary information Omp85 sequences contain, and (b) whether there is any clear evidence for lateral transfer, but not for evaluating the 'safeness' of my argument.
Therefore, in order to maximize the throughput of the Solexa technology, hence minimize its cost, it is of key importance to utilize each lane in a more sensible way, such as by sequencing more than one BAC per lane.
Analysing the diversity of known enzyme sequences is also a very sensible strategy.
Until whole genome sequencing for large cohorts becomes affordable sequencing "extended" exomes seems to provide a sensible way to reduce costs while maximizing the chances of detecting disease-associated variants.
While this approach is sensible, it rests on an implicit network clustering approach whereby sequences are first linked by sequence identity, followed by a clustering step that defines connected components in a graph and hence OTUs (see Methods).
The numbers are significantly lower than the theoretical upper limit, as most theoretically possible sequences do not produce meaningful or grammatically sensible sentences.
Eventually it will be neither practical nor sensible to conduct large-scale de novo analyses each time a new sequence is added to an alignment.
Instead of attaching barcodes to the sequencing adapters as we did, it may be more sensible in some cases to synthesise PCR primers with built-in barcodes.
