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Considering FISH data as a loss of heterozygosity measure for VAF adjusting, can lead to underestimation of VAF in those cases where 17p or 11q clones might be under the sensibility threshold established for that probe.
While TEM holds promise as a tool for use in the field, other relevant data are necessary in order to apply thrombolestometry in the detection of illicit drug treatment: the method's analytical sensibility threshold in relation to various dosages, the treatment duration, and the length of time following treatment during which altered hemostasis can still be reliably detected.
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For clinical assessment of sensibility touch threshold assessed by monofilaments (WEST) and tactile gnosis measured with the STI™ test are the most responsive tests and are recommended for future studies.
Outcome will be assessed through: pain visual analogic scale, Semmes Weinstein monofilaments™ threshold sensibility test, Pinch Gauge™, Boston Carpal Tunnel Questionnaire and two point discrimination test.
We agree that in vitro studies on Pseudomonas susceptibility may show MICs that are much lower than the upper threshold of sensibility proposed by the EUCAST for carbapenems.
Warm sensibility index was defined as: (warm pain detection threshold − warm threshold)/(warm pain detection threshold − reference temperature).
Cold sensibility index was defined as: (cold pain detection threshold − cold threshold)/(cold pain detection threshold − reference temperature).
Finally, we have also tested the sensibility of our results on the threshold in the number of calls used to consider the ties.
Pain will be assessed by the pain visual analogic scale, sensibility by Semmes Weinstein monofilaments (SorriTM, Bauru, Brazil) to detect threshold cutaneous sensibility and gnosis tactile through 2PD (North Coast, USA).
The responsiveness for sensibility tests in CTS has been reported for touch threshold [ 14].
Several of the clinical measures of sensibility showed good sensitivity to change, especially the touch threshold (WEST) and tactile gnosis (STI test).
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