Given the seminal technical progresses achieved in the last few years, it may be ready to tackle even greater challenges, namely exploring disease mechanisms.
Our program is based on two seminal developments: significant progress in our ability to analyze the molecular characteristics of individual tumors and patients (predominantly, but not exclusively, due to advancements in DNA sequencing techniques) and through the development of sophisticated computational models, which can convert this abundance of data into predictions.
(Her NLR colleague Peter Wollen practised auteurist criticism under a pseudonym before turning to semiotics, publishing a seminal book on this critical progress in 1969 called Signs and Meanings in the Cinema).
10 In addition, Bodmer and Bonilla 7 provided a historical review of the search for genetic variants influencing susceptibility of an individual to a chronic disease, from R.A. Fisher's seminal work to the current progress of whole-genome association studies.
In the following weeks, TRAMP mice over-express Tag and invariably develop spontaneous mouse prostate intraepithelial neoplasia (mPIN), which progress to adenocarcinoma and seminal vesicles, lymph node (LN) and visceral metastases, resembling human PC [26].
And at E11.5, the cortical projection neurons present firstly in PP layer and migrate to establish the seminal cortical plate (CP), which whereafter progress to form L2 L6 layers.
Despite some early success in seminal CDSS interventions for ID, little progress has been made to assist decision-making in this area [ 18, 19].
The field has progressed since Corey's seminal paper [E J Corey and W T Wipke.
The Senate should advance this seminal legislation.
Darwin published his seminal work in 1859, effectively synthesizing the progress of many biologists before him.
Our results gain in interest if we realize that the general theory of elliptic boundary value problems in domains with singular points on the boundary has made no essential progress since Kondratiev wrote his seminal paper [12].
