Sentence examples for seminal observation from inspiring English sources

Exact(25)

"I think it will turn out to be a seminal observation".

Barry Kay, emeritus professor of immunology at Imperial College London, said: "His seminal observation was that the body's responsiveness to foreign proteins [antigens] is controlled by the immune response genes he discovered.

Within malaria endemic regions, epidemiologic studies replicating Denis Burkitt's seminal observation continue to show differences in endemic BL incidence linked to intensity of malaria transmission.

The seminal observation that lectins adhered more strongly to a ligand with multiple carbohydrate binding sites initiated a plethora of studies designed to identify effective "multivalent" carbohydrate ligands for pathogens expressing multiple carbohydrate-binding sites.

About 40 years after the seminal observation of William Bayliss, Lewis [9] addressed the issue of how the skin surrounding an injured site becomes painful, by hypothesizing the existence of "nocifensor" nerve fibres.

This review is designed to describe the evolution of the seminal observation made simultaneously in 1975 by Dr. W. Haefely's laboratory (Hoffman La Roche, Basel, Switzerland) and in the Laboratory of Preclinical Pharmacology (NIH, St. Elizabeths Hospital, Washington DC), that benzodiazepine action was mediated by a modulation of GABA action at GABAA receptors.

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He made seminal observations on ion and water transport in epithelia.

He is best known for his seminal observations on the clinical-pathologic features of lupus nephritis, diabetic nephropathy, poststreptococcal glomerulonephritis, and myeloma-related renal disease, which helped form the basis of our modern understanding.

More recently, these seminal observations have even opened new potential therapeutic avenues based on the employment of adoptive T-cells somehow engineered toward potential neoplastic targets.

His seminal observations and research on influenza viruses laid the foundation for worldwide research on influenza virus structure, surveillance and subunit vaccine development.

Extensive-stage small-cell lung cancer (SCLC) patients who progress after platinum-based chemotherapy are traditionally categorized as platinum sensitive (progression ≥ 90 days from last platinum dose) or refractory (progression < 90 days), a practice arising from seminal observations of worse survival in refractory patients.

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