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In particular, we elaborate on the semantic harmonization of computational signal detection methods through an ontology model [ 55], aspiring to build a semantic registry of such methods and an integrated platform for experimentation on pharmacovigilance signal detection.
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We introduce a federated semantic metadata registry framework by extending the ISO/IEC 11179 standard, and enable integration of data element registries through Linked Open Data (LOD) principles where each Common Data Element CDEE) can be uniquely referenced, queried and processed to enable the syntactic and semantic interoperability.
The tool interacts with a semantic metadata registry through IHE data element exchange profile.
Our design is built upon the notion of CDEs and makes use of a Semantic Metadata Registry (MDR) to retrieve data element definitions and use their extraction specifications to access data [ 19, 20].
To do so, we auto-generated a class structure within SBOL-semantic that mimics the registry category structure.
In order to enable secondary use of Electronic Health Records (EHRs) by bridging the interoperability gap between clinical care and research domains, in this paper, a unified methodology and the supporting framework is introduced which brings together the power of metadata registries (MDR) and semantic web technologies.
We adapted and transformed data from the registry into SBOL-semantic, that describes standard biological parts using RDF.
Our effort, directed towards SPARQL query information retrieval, translates the existing Registry information to a Semantic Web technology standard to enhance its potential for re-use.
Once operational these services are readily findable and easy to integrate with existing semantic web services in the SADI registry.
The committee has also proposed a data category registry (DCR) where data or semantic types as labels or key-value pairs can be registered and become a standard for the field (24, 25).
The main purpose is to contribute towards the development of 'Linked Land Administration' that adopts Linked Data technologies for semantic management of datasets kept in public registries, and scholarly and legislative resources kept in libraries.
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