Plasmids coding rat HER-2 were employed because xenogeneic immunisation is an effective way to break tolerance and induce T cells and antibodies crossreacting with the self, tolerated protein (Bowne et al, 1999; Overwijk et al, 1999).
The best teachers are those who love us through our half-formed selves, tolerating our awkwardness, yet celebrating us forward.
So that left Broadway musicals as a wholesome entertainment that even my highfalutin self could tolerate.
Developing thymocytes receive a wide array of signals from thymic epithelial cells (TECs) for selection, survival, expansion, and differentiation, which can result either in cell death or in differentiated self-tolerating T cells.
Most people with broken necks don't have partners, either because they had an accident before they met one or because the strain of looking after them proved too much, was too great a sacrifice of self, to be tolerated.
To avoid indiscriminate activation and self-destruction, the immune system has developed redundant mechanisms to tolerate self or non-dangerous antigens.
Discharge was considered safe and allowed when the patient was mobile, able to self-care and tolerating a light diet.
It is more difficult to understand how the derangements of the T-cell system affect the ability to tolerate self.
At the same time, the immune system should tolerate self-antigens and innocuous non-self-antigens and allergens as uncontrolled or inappropriate responses to such antigens contribute to the pathogenic processes underlying various non-communicable diseases.
However, instead of being presented to health professionals, many symptoms are ignored, tolerated or self treated: a phenomenon known as the "symptom iceberg" [ 32].
Why is such self-criticism not tolerated today by any Arab leader?
