Sentence examples for self hypothesis from inspiring English sources
This process increases search space coverage, by generating detectors which wrap tighter around non-self hypothesis space for self detector set generation and self hypothesis space for standard AIS and non-self detector set generation.
However, NK cell-mediated cytotoxicity is "MHC unrestricted", which means that NK cells kill target cells that don't express MHC class I molecules, a guiding principle in the NK field, also known as the "missing self" hypothesis (Karre et al., 1986; Ljunggren and Karre, 1990).
The elimination of MHC class I− hMSCs by NK cells would be consistent with the "missing self" hypothesis [54] and the reported prominent role of NK cells in xenograft rejection [55].
The comparative analysis of the newly identified thirteen putative PM2-like elements, allowed us to test the innate viral "self" hypothesis [ 5, 6, 8, 13].
Comparative analysis of gene composition between the identified putative prophages and bacteriophage PM2 let us to test and support the viral "self" hypothesis.
Using the comparative genomics approach, we present evidence to support the viral "self" hypothesis and divide genes of the bacteriophage PM2 and related prophages into "self" and "nonself" categories.
However, NK cells are freed from this inhibition and have a lower activation threshold when infected or transformed cells downregulate MHC class I molecules under selective pressure to evade lysis by CD8 cytotoxic T cells (missing-self hypothesis) [ 18, 19].
The interaction of inhibitory receptors by their cognate ligands (mostly classical and non-classical MHC class I molecules) keeps NK cells inhibited, part of the "missing-self hypothesis" [ 38].
Moreover, the self-enhancement hypothesis (self-concept predicting achievement) was corroborated in early years of secondary school.
In what has become known as the "self-esteem hypothesis", self-esteem is predicted to relate to in-group bias in two ways.
3 & 4 The reduction in eating disorder features is largely mediated by an increase in general interpersonal self-efficacy (hypothesis 3) or self-esteem (hypothesis 4).
