Sentence examples for selectivity design from inspiring English sources

Further, excellent shape and size selectivity design examples are also introduced.

The recently reported X-ray structures of the human serotonin (5-HT) tranSERTter SERT with bound inhibitors open new opportunities for drug discovery at SERT, selectivity design with respect to other neurotransmitter sodium transporters, and enhanced understanding of the molecular events involved in SERT action.

IsCT-P (ILKKIWKPIKKLF-NH2) is a novel α-helical antimicrobial peptide with bacterial cell selectivity designed from a scorpion-derived peptide IsCT.

Introducing peptide bond surrogates (denoted ψ, according to Spatola's nomenclature for a class of peptide mimetics called pseudopeptides (Spatola 1983), has been long recognized as a powerful strategy for enhancing peptides' biological lifetime, improving biological activity or selectivity, designing enzyme inhibitors or inducing particular conformational features in potential vaccine candidates.

Because the gatekeeper residue is critical for kinase/small-molecule selectivity, the design of highly selective IRAK kinase inhibitors could be tractable through this unique molecular feature.

The obsession is with the budget balance, not with selectivity or design.

To yield high signal selectivity, the design of the microelectrode array has been custom tailored to match the muscle anatomy of a particular animal system, the tobacco hornworm Manduca sexta.

This review will highlight the most recent progress in the area of artificial metallonucleases employing an oxidative mechanism, focusing on the development of methodologies for cleavage detection, understanding of the factors governing the cleavage efficacy and selectivity, and design strategies for the achievement of high cleavage efficacy.

The results allowed to study in depth the structural bases for the interaction of each family of inhibitors and provided clues for further modifications, with the aim of improving the activity and selectivity of designed drugs targeting this enzyme.

Using these theoretical insights in fluid separations, a series of industrial cases was reviewed and critical aspects in technology selection, and solvent selection and design such as selectivity and capacity are discussed.

A new chemosensor for Cu2 + based on Schiff base with high sensitivity and selectivity was designed and synthesized.