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On the one hand, using fluorescent chemical probes targeting various subcellular compartments, we and others reported that dyes located at the PM rather than intracellular ones were transferred, suggesting some selectivity based on the location of labels within the cell [7], [8].
Excellent selectivity based on the molecular size of sugar was realized.
We designed novel thyromimetics with high receptor (TRβ) and organ (liver) selectivity based on the structure of eprotirome (3) and molecular modeling.
Both of these approaches have a predetermined selectivity based on the biophysical properties of the nervous tissue and membrane in the region of the stimulation.
Cavitation generated using ultrasound can enhance the rates of several chemical reactions giving better selectivity based on the physical and chemical effects.
In competitive hydrogenation of certain olefins unusual degrees of substrate selectivity based on the molecular recognition are observed, not possible by conventional transition metal catalysts.
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The transporters listed in Table 1 were selected based on the substrate selectivity in which phenylalanine or tyrosine is preferred.
For the analysis of selectivity based on personal familiarity, the ROC curves were computed from RRfamiliar and RRunfamiliar, where RRfamiliar indicates the distribution of firings in response to all of the personally familiar faces in the frontal view, while RRunfamiliar indicates the distribution of firings in response to all of the personally unfamiliar faces presented in the frontal view.
In many cases, these models provide an adequate description of enzyme selectivity based on adjustable complementarity between the active site and the cognate substrates.
This contribution addresses the possibility of controlling product selectivity based on intimate knowledge about the MTH reaction mechanisms over zeolite/zeotype materials.
This approach has provided a strong basis for the interpretation of the requirements for dopamine D1/D2 selectivity based on what is known in the field to date.
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