Suggestions(2)
Exact(4)
Under the developed Suzuki reaction conditions, when 1.1 eq of arylboronic acid was used the bromo group at 5 position was selectively substituted and a variety of mono-substituted products was synthesized (3a k) and double Suzuki cross coupling occurred by using 2.2 eq of arylboronic acids and diaryl derivatives of thiophene were synthesized (3l p) (Table 1).
Convenient laboratory procedures for obtaining selectively substituted dihydro-5H-tribenzo[a,d,g]cyclononatrienes have been achieved.
The results suggest that a few of the twelve Si sites in the framework are selectively substituted by Fe.
Anodic substitution reaction of organoboronate ester and organoborate was successfully carried out in the presence of nucleophiles to afford the selectively substituted products in good yields.
Similar(56)
To selectively substitute only one fluorine, we applied a two-step one-pot strategy, inspired by our previous work on F/F exchange on BODIPYs for hybrid optical/positron emission tomography imaging.
We reasoned further that it would be possible to differentiate between the X-group and ionization mechanisms by selectively substituting hydrogen with fluorine or other atoms in the vinylic substrate.
In this work we report the development of methodology to selectively substitute one of the two canonical fluorides common to most BODIPY dyes with alkoxy ligands, and show that the resulting dyes are highly soluble and cell permeable.
Why does the aberrant cleavage take place selectively at substituted K48 in polyubiquitins?
Cytotoxic results of curcuminoids with acetone series 1 10 and methoxy substituted exhibiting selectively more potential than cyclohexanone (11 17) and cyclopentanone (18 24) series.
The reaction kinetics are shown to be first order in model compound with the methylene-arene carbon-carbon bond adjacent to the most substituted arene being selectively cleaved.
This outcome is in line with the requirement for their prior hydrolysis and the rate acceleration observed under acidic conditions in related C H arylation reactions.[ 34] Variously substituted indoles also selectively underwent the C H arylation reaction (Scheme 2).
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