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Therefore, a vaccine based upon sequences that are naturally highly conserved in all influenza A viruses may greatly restrict the range of possible mutants that could selectively overcome immune suppression.
It is concluded that stealth® liposomal drugs selectively overcome the blood brain barrier in the tumoural areas.
Either way, this Ca2+ influx, in addition to the enhanced Rho-kinase-mediated Ca2+ sensitization, may be enough to selectively overcome opening of KV channels and cause constriction in PA.
The knowledge that spatial memory training can reverse atrophy of the hippocampus, in combination with knowledge of genetic and environmental risk factors for these conditions, may provide us with the tools required to selectively overcome predispositions to certain types of disorder.
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This substantial improvement is achieved by selectively overcoming the major shortcomings of the individual silanes.
Mitochondria-targeted therapy represents a promising approach to target tumors selectively and may overcome the resistance in current anticancer therapies.
With this method the major limitation of using PAA templates is overcome by selectively removing the dendritic ends, formed due to the inherent barrier layer thinning step required for nanowires growth.
In an attempt to devise new approaches to selective inhibitor derivatives, we describe novel bisphosphonate bone seeking MMP inhibitors (BP-MMPIs), capable to be selectively targeted and to overcome undesired side effects of broad spectrum MMPIs.
In the present review we highlight novel approaches to selectively target cancer cells and overcome drug resistance phenomena, through the use of various nanometric drug delivery systems.
So there is an essential need to develop a drug delivery system which could overcome biological barriers and selectively target the cancerous cell.
Nanotechnology seeks to use drug delivery vehicles of 1 100 nm in diameter, made up of several different materials to deliver anti-cancer drugs selectively to cancer cells and potentially overcome MDR.
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