Exact(1)
The canonical murine Treg markers, FOXP3 and CD25, do not selectively define human Tregs, since these markers can be induced on other human T cells upon activation, especially in the presence of TGFβ [12], [13].
Similar(59)
Efforts have been made to characterize different "ethnic types" among European peoples, but these are merely selectively defined physical traits that, at best, have only a certain descriptive and statistical value.
Therefore, the multi-targeted approaches are anticipated through either combination of selectively defined agents or by a single agent with multiple targets.
KYK-2.0 IgG1 was found to selectively recognize defined subpopulations of human lymphocytes known to express NKG2D, that is, the majority of human CD8+, CD16+, and CD56+ cells as well as a small fraction of human CD4+ cells.
Thus, AFLP uses PCR to selectively amplify defined subsets of DNA restriction fragments from across the whole genome.
Advances in deciphering the molecular mechanisms underlying mCRC have led to the development of novel agents that selectively inhibit defined molecular targets.
Transcranial magnetic stimulation can be applied specifically and selectively to defined cortical regions, particularly when guided by neuroimaging and physiological measures (Neggers et al., 2004; Kleim et al., 2007).
In order to perform a direct and easy quantification of transcripts on cell extracts, the feasibility of an analytical device able to selectively detect a defined target RNA in a complex mixture while avoiding labelling, retrotranscription and amplification steps, has been explored.
Using our method we were able to identify and retrieve patent documents selectively for a defined group of applicants and covering a defined field of inventions.
Thus the pro-apoptotic functioning of SIRT3 is selectively coupled with defined pathways regulating cell survival under basal conditions.
Alternatively, the green fluorescent protein (GFP) and its variants can be applied as genetically encoded intracellular probes that are specifically expressed and can be selectively targeted within defined cells and tissues.
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