These permanently exposed binding sequences thus provide a means for the cell to locally "decompress" DNA on-demand to selectively access genetic information.
The broad applicability of RNA aptamers as cell-specific delivery tools for therapeutic reagents depends on the ability to identify aptamer sequences that selectively access the cytoplasm of distinct cell types.
On a playing field leveled by OA, users can selectively access, use and cite those articles that they judge to be of the highest relevance and quality, no longer constrained by their accessibility.
Herein, we report efficient methodology to selectively access singly alkoxy-substituted BODIPYs and evaluate their applicability for live cell imaging in comparison to BODIPY and dialkoxy-BODIPY dyes.
The method is exploited further to selectively access a fluorinated combretastatin analogue in two steps starting from commercially available reagents, thus further affirming the usefulness of the protocol.
Our synthetic methodology is the first approach to selectively access MayaFluors and is compatible with a broad array of functional groups commonly utilized in chemogenomic approaches.
However, with both the booklet and the website, we expect that men will selectively access sections of interest by using the Table of Contents.
To selectively access M cells (PPK23-positive, PPK25-negative cells), we used a driver that labels both F and M cells (ppk23-LexA) while driving Gal80 with F cell drivers.
