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Codon sites under positive selection were identified using the Bayes empirical Bayes (BEB) calculation of posterior probability for site classes [ 58] that analyses the sites under positive selection identified by the selective models.
An in-depth comparative investigation was carried out between the individual and selective models to gain an insight into the selectivity criterion.
In contrast, BayeScan directly estimates the probability of each locus being subject to selection by comparing the likelihoods of neutral and selective models [ 39].
At this point, we proceed to group the student responses into nonselective models or selective models.
The selective models were found to outperform the individual models in terms of the quality of correlation and were found to be more informative in pinpointing the structural basis for the observed quantitative differences of kinase inhibition.
We consider five distinct selective models, as described in Supplementary Material Table S1.
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PTP EX and PTP ε clades were better explained by the M8 selective model and significant positively selected sites could be identified in 9 sites and 1 site, respectively (Table 1).
In contrast, the possibility of translational selection has led to the selective model, in which the choice of synonymous codons reflects tRNA abundance to optimize the efficiency and accuracy of translation.
Site-specific positive selection was tested by comparing the selective model M8 (ω>1) to the non-selective model M8a (ω = 1) by LRT [ 75].
Dr Charles Insley Canterbury Christ Church University The elitist proposals proffered by the vice-chancellor of Durham would consign a swath of universities to a financial wasteland, recreating the narrow, selective model of universities which have done little for the vast majority of people in this country.
We use both a frequency flat fading model as well as a frequency selective model.
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