Sentence examples for selective mode of action from inspiring English sources
This article is a critical review of the attempts made during the last three decades to design platinum complexes with a selective mode of action against hormone-dependent tumors.
Because of its selective mode of action, it is stated that the toxicity of 2,4-D to dicotyledonous macrophytes is underestimated by the Lemna test[8].
Several studies examined the effect of Bt crops on herbivores and arthropod natural enemies in recent years confirming the highly selective mode of action of the deployed Bt Cry proteins [12], [13].
As a consequence, new antidepressants were developed with a more selective mode of action, which mainly aimed at avoiding these side effects.
Moreover, these four clusters are equally identified when using two different metrics as activity cutoff, further confirming their selective mode-of-action as compared to other clusters.
Acylated cyclic peptide inhibitors of β(1,3 glucan synthesis with origins as fungal metabolites provide an alternative and highly-selective mode of action, targeting cell-wall biogenesis in important pathogens such as Candida and Aspergillus species.
Triton X-100, monolaurin, DDPS and SDS were toxic to all cell types at concentrations around their critical micelle concentration (CMC) suggesting a non-selective mode of action involving cell membrane destabilization and/or destruction.
As PKC ɛ is overexpressed in tumor cells, a tumor cell-selective mode of action is proposed.
Future screens of synthetic libraries of short peptides with anti-cancer potential in zebrafish embryos hold great promise for finding the highly selective and active variants, and for discerning their mode-of-action.
Calcein dye leakage and transmission electron microscopic studies with model membranes exhibited selective membrane active mode of action for peptide SA-3 and SA-4.
This creates somewhat of a paradox as elongation inhibitors are not expected to be selective in their mode of action and would be expected to possess a narrow therapeutic window.
