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Sexual selection could therefore be a selective mechanism that enhances or contributes secondary to the diversification of reticulation patterns at high altitude in some species [20] [22].
Although we just tested a few chemoattractants we suggested that chemotaxis impairment in presence of Pebisut is not a selective mechanism and would be more related with mechanical impediment as we explain.
In that paper, he argued that sleep isn't crucial just for memory consolidation; it is also a remarkably selective mechanism.
This selective mechanism could decrease off-target accumulation of 4 and, consequently, Pt-associated side-effects.
Therefore, the formose reaction must still be considered to be of great potential if we could identify some selective mechanism that would interact with it.
The proposal of this selective mechanism could be helpful for the rational design of novel selective inhibitors of the Polycomb CBX protein.
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As for cytochrome P450 enzymes, a variety of irreversible inhibitors proved to be selective mechanism-based inactivators (suicide substrates) through their chemical modifications of the CYP heme and/or heme-thiolate proteins.
Importantly, more than 70% of untransformed MCF-10A cells were still viable even with 200 μM C-6 treatment which further supports a cancer selective mechanism-of-action.
Although the mechanism remains to be clarified, exogenous α-synuclein fibrils may enter cells through a selective mechanism s), such as neuron-specific receptors.
In this study, we performed two pairs of microsecond molecular dynamic simulations (CBX2 (-UNC3866)) and (CBX7 (-UNC3866)) to study the inhibition and isoform-selective mechanism of UNC3866 to CBX7.
In mammals, macropinocytosis is a potent non-selective mechanism of antigen uptake limited to immature dendritic cells and their myeloid progenitors, and monocytes/macrophages activated by exogenous stimuli [25], [26].
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