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We propose that the engineering of enhanced stability may also be accomplished through selective engineering of the protein periphery rather than by redesigning its entire core.
In this context, in this study, the correlation between heparin binding affinity and cell proliferation activity of hFGF1 is examined by extending the heparin binding pocket through selective engineering via charge reversal mutations (D82R, D84R and D82R/D84R).
We conclude that coding sequences can be re-wired for high-level protein expression by selective engineering of the 5′ coding sequence with synonymous codons, thus circumventing the need to consider whole sequence optimization.
Founded on the premise that brilliance is evenly distributed but opportunity is not, Andela has built one of the most selective engineering institutions in the world, with headquarters in Lagos, Nairobi, and NYC.
If you're aiming for a very selective engineering job (e.g. Facebook, Google, Amazon, etc), then you'll probably want to dedicate a few weeks (or more) just to fine-tuning your technical interview skills.
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The part about selective breeding and engineering when it comes to shrimp is pretty interesting.
Although successful in selective treatments, tissue engineering needs to overcome major challenges to allow widespread clinical application with predictable outcomes.
Selective surface energy engineering was achieved by combining conventional photolithography and local hydrophobic treatments with a self-assembled monolayer (SAM) at the exposed surface.
To date, I've worked on developing bacterial viruses (called bacteriophages) as selective antimicrobials, on engineering commensal Bacteroides species as therapeutics for inflammatory bowel disease, and on creating a hybrid bacterial-electronic medical device to measure biomarkers associated with gastrointestinal health.
DNA based nanotechnology, in many ways, has been one of the most intensively studied fields in recent years that involves the use and the creation of bio-inspired materials and their technologies for highly selective biosensing, nanoarchitecture engineering and nanoelectronics.
Indeed, even going out of one's way to create a disabled child (through genetic engineering, selective abortion, or preimplantation genetic diagnosis) cannot count as harming the child, since that particular child has no options for existing other than as disabled.
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