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Successful application of BNCT requires selective delivery of 10B to the tumor [1, 6].
This selective delivery of the drugs has been called target treatment.
MNTs are recombinant multifunctional polypeptides that we have developed for achieving selective delivery of short-range therapeutics into cancer cells.
This platform enables targeting cancer cells and selective delivery of highly cytotoxic drugs, resulting in a broad therapeutic window.
In conclusion, our studies showed selective delivery of dexamethasone to KC with Dexa5-Man10-HSA.
Currently, despite the great success in the targeted therapy, the problem of selective delivery of AuNPs in the target tissue remains unsolved.
The concept of selective delivery of toxic agents to target cells causing disease was originally proposed in 1913 by German physician and scientist Paul Ehrlich (Ehrlich, 1913).
Boron neutron capture therapy (BNCT) requires selective delivery of 10B-containing drug to the tumor and irradiation of the tumor with neutrons.
Liposomal contrast agents having Gd III) are known as a nano-contrast agent system for the efficient and selective delivery of contrast agents into pathological sites.
These results support our central hypothesis that PAP-1 may enable the selective delivery of macromolecules to tumors.
Nanotubes may serve as non-immunogenic containers of biocompounds and vehicles for selective delivery to the cell membrane.
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