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Anion binding studies carried out using fluorescence spectroscopy and 1H NMR revealed that this compound displays selective affinities for iodide ion.
Nevertheless, these antagonists do not display selective affinities for distinguishing amongst their corresponding α1- and α2-adrenoceptor subtypes (Table 1).
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This demonstrated that V2 and V3 fHbps displayed no selective affinity for CFH over CFHR3 (average selectivity being 1.8 ± 1.4 and 2.4 ± 1.0, respectively).
Hanshaw, R. G., Lakshmi, C., Lambert, T. N., Johnson, J. R. & Smith, B. D. Fluorescent detection of apoptotic cells by using zinc coordination complexes with a selective affinity for membrane surfaces enriched with phosphatidylserine.
While still a student, Ehrlich carried out some work on lead poisoning from which he evolved the theory that was to guide much of his subsequent work that certain tissues have a selective affinity for certain chemicals.
The aryloxyanilide derivatives, which have been derived by opening the diazepine ring of 1, are a novel class as PBR ligands and have exhibited high and selective affinity for peripheral benzodiazepine receptors (PBRs).
This paper reports the development of a pH-responsive molecular pattern that shows specific and selective affinity for particular host-guest interactions, and its use as a pH fluorescent sensor.
The generation of this NGF variant with selective affinity for p75NTR can be used to enhance understanding of neurotrophin receptor imbalance in diseases and identifies a key targetable residue for the development of small molecules to disrupt binding of NGF to TrkA with potential uses in chronic pain.
In the search for nicotinic acetylcholine receptor (nAChRs) agonists with a selective affinity for the homomeric α7 channels, we carried out the virtual screening of a test set of potential nicotinic ligands, and adopted a simplified MM-PBSA approach to estimate their relative binding free energy values.
The compounds, reported in Figure 17, show highly selective affinity for Pb II) ions over a range of other metal ions, through different channels, i.e., as redox, chromogenic, and fluorescent chemosensors.
The formula of this silica-bending peptide is CALNNGMSPHPHPRHHHT [13], hereafter noted CALNN-Si-peptide, and the peptide which has a selective affinity for carbon nanotubes is CALNNGHWKHPWGAWDTL [14], hereafter noted CALNN-Carbon-peptide.
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