As a result, a careful control of the reaction temperature during the substitution reactions will allow the synthesis of 2,4,6-trisubstituted-1,3,5-triazines by the sequential and very selective addition of amine nucleophiles [1, 43].
Especially important is the impact of the presence of oxygenates on the course of the process and possibility to manipulate the product spectrum by selective addition of oxygenates [55]-[61] [55]-[61]
In this feature article, we describe the synthetic work in our laboratory on branched polymers through anionic polymerization reaction based on selective addition of organolithium toward a bifunctional 1,1-diphenylethylene derivative, 1,3-bis 1-phenylvinyl benzene (MDDPE).
The high strength concretes are manufactured invariably by the selective addition of several mineral admixtures like silica fume, metakaoline, flyash, rice husk ash, ground granulated blast furnace slag, etc.
Thus, introduction of the DOTA moiety was achieved through its selective addition to the β or ε side chain amino group of a Dpr or Lys residue, respectively, introduced at position 29 which was found to be tolerant to amino acid replacement [25, 26].
The current study extends these results by demonstrating that the selective addition of AMPAR-mediated plasticity to CA1 pyramidal cells impairs NMDAR-dependent learning.
