Sentence examples for selection stringency from inspiring English sources

The selection-only model proposes that relaxed selection stringency allows small-effect mutants to initiate slow-growing clones on selective plates.

We report on the influence parameters including droplet occupancy, valency and selection stringency have on recovery and enrichment.

Thus, SJ enhances negative selection stringency and can accelerate allelic replacement in pneumococcus, especially when transformation frequency is low due to strain background or suboptimal transformation conditions.

The selection stringency was significantly increased, as indicated by the shift towards higher distribution of producing-cell populations, even with no MSX added into cell culture medium.

Previous studies have shown significant improvement in selection stringency by using GS-knockout CHO cells, which eliminate background GS expression from the endogenous GS gene in CHOK1SV cells.

To further improve selection stringency, a series of weakened SV40E promoters have been generated and used to modulate plasmid-based GS expression with the intent of manipulating GS-CHO selection, finely adjusting the balance between GS expression and GS inhibitor (MSX) levels.

This is largely due to low selection stringencies, creating many, but low protein producing clones.

Thus, the p1.1 plasmid is suitable for creation of stably transfected cell clones or populations under variable selection stringencies.

Thinning is expected to reduce the extent of covariance and collinearity that otherwise occur in base QTL analyses with the dense maps and/or relaxed selection stringencies.

For rounds 7 through 12, counter-selection stringency was increased by raising the adenosine concentration to 1.0 mM.

They suggested that there might be some value in assessor training or selection, since stringency variation tells us something about the internalized standards of the assessors.