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However, neither of the transduction efficiency or the selection specificity is expected to be completely 100%.
Here, we discuss the potential of ecogenomics approaches in developing high-throughput methods for detecting and monitoring organohalide respirers, and for providing improvements to selection, specificity and sensitivity of target biomarkers and their application to evaluate bioremediation strategies.
Coincidence check was employed to enhance selection specificity.
A single mismatch within the first four nucleotides of an siRNA duplex is sufficient to determine strand selection specificity.
Although Cas9 uses complementarity between the gRNA and the target DNA to determine cleavage site selection, specificity is not absolute [45,46].
Finally, as strand selection specificity can result in enormous expression level differences within some miRNA pairs, which in extreme cases can exceed one million copies, it is tempting to speculate that some of the sequence features we find may actively target the excluded miRNA strand for degradation.
Similar(53)
Serum specific peptides were selected by two rounds of iterative affinity selection and specificity of phages for different mouse sera was assessed by dot blot (according to the method described in [40]).
SDPclust performs best in terms of selection of specificity groups, including the difficult case of the generated family 2, where other methods fail.
This therefore suggests that even in the presence of strong links between the two species (i.e., strong selection, high specificity, etc)., antagonistic coevolution need not result in fluctuations of genotypes and phenotypes.
On the other hand, where the second plant carries a different resistance specificity, selection on the pathogen will switch immediately to mortality selection with only individuals with the appropriate infectivity genes surviving.
In this process, the E3 ligases are responsible for substrate selection and the specificity of Ub-linkage.
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