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The SRE selected on the basis of waveform similarity excludes bias by the selection of sequence; the models using the Bayesian approach and small sample theory adapt fairly well to small samples and the open-ended interval.
Rather, we suggest that a more global shift has occurred, independent of selection of sequence changes.
For X-chromosomal genes expressed in testis, Khaitovich et al. (2005) suggested positive selection of sequence changes as well as expression changes, leading to the X chromosome showing the highest number of expression changes between human and chimpanzee across all chromosomes in testis [30].
This implies a remarkable shift towards lower expression of a large number of X-linked genes in chimpanzee testis, and it can be questioned what is the biological rationale behind positive darwinian selection of sequence changes acting towards such a lower expression.
Then a series of E-value thresholds were applied for the selection of sequence pairs with significant similarity.
Within TCGA alone, issues affecting the quality of sequence data range from sample collection to selection of sequence alignment tools: Biological sample collection.
Similar(49)
In the course of upgrading the performance of the second-generation sequencers, the best-subset selection of sequencing data would be more important to make a good assembly of bacterial genome.
Gene prediction and the selection of sequences for oligonucleotide probes were based on sequenced contigs of the P. pastoris genome including predictions of protein coding genes, available through Integrated Genomics [ 8].
For each of the 94 HomFam families we selected the HOMSTRAD reference sequences and a random selection of sequences to make up 1000 sequences in total.
We chose three different negative sets: a random selection of sequences from the genome, a randomly selected set of promoters, and shuffled versions of the held-out sequences.
Influence of element stability on selection of sequences supporting the fold of a globular protein; or, why some protein structures occur frequently while others are rare.
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