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The National Institutes of Health has awarded $12.7 million to match nine academic research groups with a selection of pharmaceutical industry compounds to explore new treatments for patients in eight disease areas, including Alzheimer's disease, Duchenne muscular dystrophy and schizophrenia.
We will introduce the methodology and illustrate its application using a selection of pharmaceutical compounds, one of which will be Abbott's well-publicised anti-HIV medication ritonavir (Norvir™).
In this paper, we discuss a selection of pharmaceutical policy choices available to governments that may lead to improved access to medicines.
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A roadmap for the selection of a pharmaceutical salt form for a development candidate is presented.
The design and selection of new pharmaceutical dosage forms involves the careful consideration and balancing of a quality target product profile against technical challenges and development feasibility.
Matrix effects are also compared with ESI on a refined selection of 19 pharmaceutical and biological compounds in 4 matrices commonly encountered in bioanalysis.
A crucial step in the development of therapeutic monoclonal antibodies is the selection of robust pharmaceutical candidates and screening of efficacious protein formulations to increase the resistance toward physicochemical degradation and aggregation during processing and storage.
The availability of crystal structures for the ligand binding domains of ionotropic glutamate receptors, combined with their key role in synaptic function in the normal and diseased brain, offers a unique selection of targets for pharmaceutical research compared to other drug targets for which the atomic structure of the ligand binding site is not known.
Particular attention must be devoted to the selection of starch, a pharmaceutical excipient generally used in vaginal formulations [ 58], for effective binding of the virus entry inhibitors from PJ.
Governance of the pharmaceutical sector is related to eight functions (Kohler and Baghdadi-Sabeti 2011): registration, selection, procurement, distribution, licensing of pharmaceutical establishment, inspection, control of promotion and control of clinical trials.
The efficient and safe selection, procurement, storage and delivery of pharmaceutical commodities are essential functions in ensuring sustained global health outcomes, especially in resource-poor settings.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com