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The approach effectively avoided the selection of false positive results.
To achieve this aim, an Integer Linear Program (ILP) is proposed for the optimal selection of false positives.
This might lead to selection of false positives during MAS.
dChip revealed slightly less true positives and presented a small but constant selection of false positives.
44 This misdiagnosis may have represented an important bias in the selection of "false" CM isolates of P. falciparum in previous genetic studies.
The cDNA probe concentration used in the various hybridization experiments could provide another factor in the selection of false negatives in NSH.
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In our study, the selection of false-positive SNPs should have been prevented by the use of trace data for SNP detection [33], and a set of stringent criteria including MAF and contig size.
Selection of "false-negatives" can be attributed to experimental limitations common to hybridization screening.
Sgnificantly differentially expressed genes were determined with a selection threshold of false discovery rate, FDR<5% and fold change ≥2.0 (significant induction) or ≤0.5 (significant repression).
Tissue-enriched genes were identified by the following procedures: The microarray data were subjected to preliminary screening with a selection threshold of false discovery rate (FDR) less than 5% using a multiclass method in the SAM software.
Along with the multiple testing problem, the primary drawback of the single-locus filter methods is that they do not take account of the interactions between the features, which may lead to selection of both false positives, such as redundant loci, and false negatives due to epistasis interactions between or within loci [ 12, 13, 15].
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