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Because our primary aim was to identify protein candidates involved in sperm-egg interactions, we extracted only the proteins that contain a signal sequence and/or transmembrane domain [ 14] by selecting signal peptide and transmembrane features from sequence annotation (features) in an extensively curated UniProt database (www.uniprot.org) (for more details refer to [ 4, 5]).
The developing thymocyte has a window of opportunity during which to sample a variety of ligand/MHC complexes and receive a positively selecting signal before it undergoes programmed cell death, but the signals maintaining thymocyte viability and the pathways that control cell survival or death in response to these interactions are not well understood.
Although we generally found little correlation between signal peptide sequence properties and secretion results, our genome-wide data do suggest some criteria that may be used to increase the likelihood of selecting signal peptides (SPs) that yield efficient secretion of heterologous proteins.
Likewise, a coronin-1A-dependent readjusting of F-actin dynamics in proportion to the strength of the selecting signal may be required as T cells eventually acquire a functional immune repertoire.
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The effects of interactions between spikes is minimized by selecting signals that generate spikes with relatively long interspike intervals (ISIs).
By selecting signaling nodes, the plot is populated by the marking series values for individual nodes over time, as shown in Figure 8(c).
Based on the identified flux distributions or linear combinations, the user can simulate the NMR and GC/MS spectra of selected signal molecules.
Specifically, the selected signal is obtained by means of a stable nominal dynamic inversion that uses the known "steering along zeros control" concept.
Characteristics of the selected signal part laying in are employed to choose its resampling frequency.
Two techniques are described to filter the selected signal obtained at the ASA output.
We used the preference score as the index of the evaluation, which is the frequency of the selected signal.
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CEO of Professional Science Editing for Scientists @ prosciediting.com