Dr. Jeffrey P. Kahn, director of the Center for Bioethics at the University of Minnesota, said, "We've crossed the line that we really never had crossed before, selecting based on characteristics that are not the best for the child being born, but for somebody else.
So we're definitely selecting based on those that can go further on the capital they raise.
However, we minimise this potential bias by selecting based on citation count (i.e., 10 or more), source (i.e., all journals) and including recent conference papers (i.e., from 2013 and the latest 20 from 2012).
GS aims to accurately predict breeding values with genome-wide marker data using a three-step process: (1) model training and validation, (2) predicting breeding values, and (3) selecting based on these predictions (Heffner et al., 2010).
This reflects the fact that all participating flocks were members of the NSP and, hence, would have been selecting based on PrP genotype and, in particular, against the VRQ allele, possibly for several years prior to recruitment [ 31].
When identifying patients for primary prevention of cardiovascular disease, selecting patients for cardiovascular risk assessment using a prior estimate of cardiovascular risk is clearly a more efficient strategy than selecting based on other criteria.
