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The important part is in selecting a novel mission that will be a stretch to achieve.
Thus, before selecting a novel vitamin D3 analogue for drug development, several different aspects and properties of a compound must be considered.
However, high potency to activate the vitamin D receptor or inhibiting keratinocyte proliferation, are only some parameters to consider before selecting a novel vitamin D3 analogue for further drug development.
One end of the apparatus was used for the sample phase while at the other end the rat was rewarded with food for selecting a novel object rather than the familiar sample object.
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He finally secured funding and selected a novel genetic approach: he would chemically induce genetic mutations in yeast cells, then isolate those mutant cells that had malfunctions in the transport and secretory system.
Thin-layer chromatography of three biosurfactants was performed on pure silica gel plate and silica gel G impregnated with different concentration levels (0.1~10%) of 1-methylimidazolium chloride using four mobile phases (M1-M4) in order to select a novel TLC system for achieving separation of three coexisting biosurfactants.
In the future, we may apply the prognostic indices to estimation of risk of recurrence for serous ovarian cancer patients and select a novel treatment such as dose-dense chemotherapy [39] or molecular-targeted agent for the purpose of improving prognosis of high-risk patients.
We investigated whether long-lasting artemisinin pressure selects a novel multidrug-tolerance profile.
The DNMS task is based on the discovery that, by using a rewarded forced-choice procedure, monkeys can rapidly be trained to select a novel object in preference to a familiar object, i.e., demonstrate recognition memory.
We selected a novel motor resting HBD task that addresses certain methodological limitations of previous reports, such as working memory load and external stimulus interference during interception (Additional file 1: 2.2).
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