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A portion of the current population is randomly selected to be mutated.
If an element a i is selected to be mutated, its value changed as a i ′ = a i - δ ( t, a i - L i ), random 0,1) < 0.5, a i + δ ( t, U i - a i ), random 0,1) > 0.5.
There is a general nomenclature "DE/x/y" developed to denote the different DE mutant variants, where "DE" means differential evolution, "x" indicates which individual as the base vector is selected to be mutated, and "y" is the number of difference vectors chosen for perturbation of x.
For the interaction with the second hydroxyl group, the residue selected to be mutated is Arg 73.
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In order to explore the large search space of graph topologies, these reproduction operators are designed to be unbiased so that all nodes in a graph have equal chances of being selected to be swapped or mutated.
The two boxes show subsets used for selecting fragments to be mutated.
First, the part to be mutated was randomly selected, and we then randomly selected a triplet to replace the mutated part.
To submit a mutation, the user selects the source amino acid residue which needs to be mutated with the desired residue.
In 55 (92%) samples codon 12 was found to be mutated.
Conserved subsequences often correspond to active sites which cannot be mutated, so variations in that subsequence are selected against.
They can be mutated, crossbred, and cloned.
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