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The effects of the selected strata in the minimization algorithm on the primary and secondary endpoints will be evaluated additionally.
Cox proportional hazard assumptions were tested by visual examination of log-minus-log plots showing parallelism among the selected strata variable (responding status).
Furthermore, although in our study design we excluded lower (forms 1 and 2) secondary schools students among the selected strata, authors do not feel that such exclusion leads to potential bias.
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The selected stratum is further split into four strata.
Further, the segmentation and clustering algorithm's parameter choices, including the significance thresholds, are preset at the outset, and therefore the proposed procedure is free from the biases due to "artificial" human interventions, such as halting the algorithm at will to secure selected stratum boundaries as was done previously (Kelkar et al. 2009).
Four intervention carry-outs were randomly selected per strata.
In accordance with international requirements, the study focuses on selected age strata.
An estimated sample size of 2,000 adults randomly selected among strata of equal sizes was calculated on the basis of an expected prevalence of HCV infection of 6.3%, 95% confidence level and precision level of 3% [ 17, 21].
The goals of this analysis were: to examine how closely population estimates for the year 2000 from the California DOF correlated overall and for selected population strata with counts from the 2000 US census; and to assess how breast cancer incidence rates in selected California counties could be affected by the error of closure between DOF estimates and census counts.
Women with complete information on lead biomarkers and the relevant genotypes were randomly selected by strata of race/ethnicity and VDR genotype (by the Fok1 restriction enzyme) to ensure that we had approximately similar numbers of subjects in each race/ ethnicity and VDR Fok1 genotype category.
We randomly selected one stratum-matched control for each case from those men who had provided a non-fasted blood sample at the prostate check clinic.
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