(2) Standard LASSO implicitly assumes a sparse structure in the covariates, and hence tends to select insufficient confounders in high-dimensional regression, which in turn leads to an inflated false positive rate.
If a patient selects an insufficient level of adherence (e.g., several missing doses; in practice this occurs rarely), the HIV-nurse explores the reasons for this with the aim to motivate the patient to strife for a safe level of adherence.
The second explanation holds that evolution only selects against insufficient stability, but that proteins typically are marginally stable because most mutations are destabilizing and so extra stability is rapidly eroded by functionally neutral but destabilizing mutations (Taverna and Goldstein, 2002; Bloom et al., 2007).
The data is collected from limited to small, nonrandomly selected areas with insufficient focus on global carbon research (Brown et al. 1989).
Rule 2: If the number of samples in the selected layer is insufficient, i.e. the number is less than a threshold value α (α is set as 8 in Fig. 1), the correlation between factors is ignored and the independent distribution of the corresponding factor is used directly.
1) Insufficient differential in expression, e.g. Wnt11 and Wnt7b, regarded as specific to the ureteric tip and collecting duct respectively, were not selected due to insufficient differential expression between this and all other compartments.
A recent NIH workshop on combination drug therapy for TBI concluded that past failures in clinical trials resulted, in part, from preclinical testing that selected drugs with insufficient potency [2].
Despite having reports of more than 100 cases every year, tuberculosis and malaria were not selected because of insufficient information.
Unfortunately information on methodological quality of selected studies was insufficient to allow a detailed analysis of their quality.
The ascertainment bias (the systematic distortion in measuring the true frequency of SNPs due to sampling) introduced in the marker development phase may have selected markers with insufficient variation outside V. vinifera or phylogenetic depth, and differences may be distorted due to domestication.
