Different research opportunities can be derived from these white spots, as these and the resulting research opportunities are not intended to be exhaustive, but rather should highlight the selected gaps within the framework.
In order to obtain a more complete understanding of the fatigue performances of these two joint types, the maximum stress concentrated factor (SCF), the hot spot stress (HSS) and the predicted fatigue life for a set of selected gapped and partially overlapped CHS K-joints which cover a wide range of geometrical parameters are determined and compared.
DNA from BAC clones known to span the selected gaps was used if PCR resulted in no amplification or complex band patterns when using genomic DNA, and to confirm positive results.
In this review we discuss the principles in discovery and development of GAPs in preclinical models that are important in selecting GAP parasites for first-in-human clinical studies.
In particular, we explored two possible strategies (i) minimize the effect of guide-tree dependency and (ii) select gaps that are more likely to contain true phylogenetic information (use of consistency-based alignment trimming).
To do so, we investigated whether consistency-based trimming, as the one implemented in trimAl v1.3 (Capella-Gutierrez et al., 2009), served to select gaps that are more likely to contain true phylogenetic information.
For equally parsimonious gap parameters, selected parameters (gap opening penalty of -1,000 and gap extension penalty of -10) were used so that known "young" transposition events were treated as a single insertion/deletion event.
It was found that there is a critical anti-gap spacing for a selected finger gap at which the device sensitivity is the highest (ratio of 3.45: 1).
The poet, translator, and publisher Rosmarie Waldrop, who turned eighty last year, has condensed her nearly twenty books of verse into a volume of selected poems, "Gap Gardening" (New Directions).
