Exact(7)
The technique consists of a stepwise selection process whereby small sets of neighboring residues are randomized using degenerate DNA cassettes that encode all 20 naturally occurring amino acids, selected for function, and sequenced to identify acceptable substitutions.
The statement that motifs are selected for function has two possible interpretations, not necessarily incompatible: 1.
According to this model the homing endonuclease is selected for function only during the spreading phase of the parasite.
The phylogenetic footprints suggest that the HH region of the pDo500 sequence family is selected for function in Dolichopoda cave crickets.
The inference that these motifs have been selected for function rests on the idea that their occurrences are significantly more frequent than random.
Especially, three genes (Cs4g18005, Cs6g08730 and Cs8g04820), which expressed responsive to two or more different stress conditions, have been selected for function studies through over-expression and RNAi knockdown strategy.
Similar(53)
The duplication of Sry on the Rattus norvegicus Y-chromosome has led to proteins with altered functional ability that may have been selected for functions in addition to testis determination.
The 1,536 CpG sites examined were located in 740 loci that were selected for functions in cell growth, proliferation or embryonic development [ 32].
Although the vector is amplified by PCR using a high-fidelity polymerase, mutation(s) could occur during the amplification; however, the cloning system directly selects for function of essential vector components (i.e. selectable marker, origin of replication).
Screening or selecting for function has in turn led to schemes for the directed evolution of biomolecules.
Plant genotype probably selects for function rather than microbial lineage, and even though 16S rRNA gene sequence data can be used as a proxy for function, these inferences are limited.
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